Independent Brand Partner with Nerium International. Nerium's skincare products are rooted in nature, science, and high-impact ingredients. Our flagship product, NeriumAD Age-Defying Treatment, contains the most effective ingredients available, including our exclusive, patented NAE-8 extract, which has powerful antioxidant properties that help reduce the appearance of many signs of aging. This night cream has higher concentrations of the NAE-8 extract and our proprietary protein blend than any product in the NeriumAD line. These high-impact ingredients help the skin appear youthful and tight. Over one million people have enjoyed the benefits